Iron Addicts Way of Change

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Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer.

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Mol Cancer Ther ; 9 : — Aldehyde dehydrogenase in combination with CD defines angiogenic ovarian cancer stem cells that portend poor patient survival. Cancer Res ; 71 : — Karst AM, Drapkin R. Ovarian cancer pathogenesis: a model in evolution.

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J Oncol ; : Ng A, Barker N. Ovary and fimbrial stem cells: biology, niche and cancer origins. Nat Rev Mol Cell Biol ; 16 : — In vitro and in vivo correlates of physiological and neoplastic human Fallopian tube stem cells. Iron and cancer: more ore to be mined. Nat Rev Cancer ; 13 : — Ironing out cancer. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells.

Cancer Cell ; 3 : — Advances in serous tubal intraepithelial carcinoma: correlation with high grade serous carcinoma and ovarian carcinogenesis. Int J Clin Exp Pathol ; 7 : — Kurman RJ.

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Origin and molecular pathogenesis of ovarian high-grade serous carcinoma. Ann Oncol ; 24 Suppl 10 : x16—x Dietl J.

Revisiting the pathogenesis of ovarian cancer: the central role of the fallopian tube. Arch Gynecol Obstet ; : — IRP2 regulates breast tumor growth. Cancer Res ; 74 : — Gershenson DM.

The life and times of low-grade serous carcinoma of the ovary. Regulation of ferritin genes and protein. Blood ; 99 : — Oncogene ; 28 : — Snail and slug mediate radioresistance and chemoresistance by antagonizing pmediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells. Stem Cells ; 27 : — The PAX2-null immunophenotype defines multiple lineages with common expression signatures in benign and neoplastic oviductal epithelium. Gynecol Oncol ; 38 : — Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary.

J Pathol ; : 49— Iron and Cancer: recent insights. Ann NY Acad Sci ; : — Evaluating cell lines as tumour models by comparison of genomic profiles. Nat commun ; 4 : Blood ; : — Functional consequences of ferroportin 1 mutations.

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Blood cells mol dis ; 35 : 33— The biology of ovarian cancer: new opportunities for translation. Nat Rev Cancer ; 9 : — Leinster DA, et al. Full Name Comment goes here. Are you sure you want to Yes No.

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Iron addiction: a novel therapeutic target in ovarian cancer

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Iron Addicts: CT Fletcher's Supplement Line is KILLER

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